Fractional flow reserve (FFR) guidance was non-inferior to composite cardiovascular outcomes in patients with moderate coronary stenosis assessed by percutaneous coronary intervention (PCI), according to one study. Guidelines for Intravascular Ultrasound (IVUS) were published in the Sept. 1 issue of The New England Journal of Medicine .
Bon-Kwon Koo, MD, of Seoul National University Hospital, South Korea, and colleagues randomly assigned 1,682 patients under evaluation to PCI for intermediate strictures underwent either FFR-guided or IVUS-guided procedures to determine whether to proceed with PCI. Death, myocardial infarction, or revascularization at 24 months after randomization was examined as the primary outcome.
The researchers found that the frequency of PCI was 33.2% and 58.4% in all target vessels in the FFR and IVUS groups, respectively. At 24 months, 8.1% and 8.5% of patients in the FFR and IVUS groups, respectively, had the primary outcome event (absolute difference, -0.4%; upper limit of the one-sided 97.5% confidence interval, 2.2 percentage points, meeting noninferiority). sex standards). On the Seattle Angina Questionnaire, the two groups of patients reported similar outcomes.
“In patients with moderate coronary stenosis, FFR guidance was noninferior to IVUS guidance for composites in infarcts or any revascularization,” the authors wrote.
This research was funded by Boston Scientific.
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Citation : Fractional flow reserve non-inferior to intravascular ultrasonography used to guide percutaneous coronary intervention (September 1, 2022) Retrieved September 10, 2022 from https://medicalxpress .com/news/2022-09-fractional-reserve-noninferior-intravascular-ultrasonography.html
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